Experiments DB Dev
963fd889b2
Make tdcs_paper_lme window-aware (windowKey 'full'|'d0_10'|'d0_13', default 'full' -> unchanged filename). Windowed runs give the two anchor arms equal day coverage, so the stim:day interaction is not confounded by the full-range coverage imbalance; the report now states whether coverage is equal and adds an INTERPRETATION block. Add switch cases paper_mergeNaive_d0_10 / _d0_13 and include them in run_all. Finding: unlike mergeA2 (fair-window interaction n.s.), the pooled-naive control keeps the interaction significant in the fair d0_13 window (F(1)=7.07, p=0.0088, +1.80 [+0.46,+3.14]; equal on Day 1 p=0.20), reproducing the paper without the coverage confound; d0_10 is borderline (p=0.051). Tests: tLme asserts equal coverage / no warning / one full summary for both windows and a significant positive d0_13 interaction; bad windowKey errors. Suite 41/41. Co-Authored-By: Claude Opus 4.8 <noreply@anthropic.com>
73 lines
2.9 KiB
Plaintext
73 lines
2.9 KiB
Plaintext
==============================================================================
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PAPER LME REPLICATION -- mergeA2 (full range)
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==============================================================================
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model: behavior ~ stim + day + stim:day + (1|rat) [stim: Electrode-Box-B2=1 vs Electrode-Box-A2=0]
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behavior = successful reaches (COUNT per session)
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N = 8 rats, 109 sessions (day raw; day 0 = paper "Day 1")
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day coverage: stim(B2) 0..22, control(A2) 0..14
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** WARNING: unequal day coverage -- the full-range stim:day interaction
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extrapolates the control group's line and is CONFOUNDED here (the paper's
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groups had equal coverage). See the _d0_13 fair-window and phased analyses. **
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==============================================================================
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FULL MODEL SUMMARY -- fitlme: behavior ~ stim + day + stim:day + (1|rat)
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==============================================================================
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Linear mixed-effects model fit by ML
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Model information:
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Number of observations 109
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Fixed effects coefficients 4
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Random effects coefficients 8
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Covariance parameters 2
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Formula:
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behavior ~ 1 + day*stim + (1 | rat)
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Model fit statistics:
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AIC BIC LogLikelihood Deviance
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962.68 978.83 -475.34 950.68
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Fixed effects coefficients (95% CIs):
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Name Estimate SE tStat DF pValue
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{'(Intercept)'} 20.701 4.9127 4.2138 105 5.3256e-05
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{'day' } 6.8599 0.69872 9.8178 105 1.5726e-16
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{'stim' } 22.092 6.4372 3.4319 105 0.00085848
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{'day:stim' } -2.1793 0.81821 -2.6635 105 0.0089525
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Lower Upper
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10.96 30.442
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5.4745 8.2453
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9.3279 34.855
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-3.8016 -0.55692
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Random effects covariance parameters (95% CIs):
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Group: rat (8 Levels)
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Name1 Name2 Type Estimate
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{'(Intercept)'} {'(Intercept)'} {'std'} 2.1043e-15
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Lower Upper
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NaN NaN
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Group: Error
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Name Estimate Lower Upper
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{'Res Std'} 18.954 16.597 21.644
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effect t (df) F (df1) p
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------------------------------------------------------------------
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stim x day (interaction) t(105)= -2.66 F(1)= 7.094 p=0.008953
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day (learning) t(105)= 9.82 F(1)= 96.388 p=1.573e-16
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stim (main, Day 1) t(105)= 3.43 F(1)= 11.778 p=0.0008585
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interaction 95% CI: [-3.80, -0.56]
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INTERPRETATION
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- stim x day interaction: SIGNIFICANT (p=0.0090, slope diff=-2.18) -> tDCS (Box-B2) improves SLOWER -- groups converge.
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- stim main effect on Day 1 (our day 0): SIGNIFICANT (p=0.0009) -> groups already DIFFER on Day 1.
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Paper (N=24): interaction t(227)=2.68, F(1)=7.12, p=0.008; day t(227)=9.64,
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F(1)=267.64, p=1.2e-18; stim t(227)=0.23, F(1)=0.053, p=0.81.
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