0e16690c8f
Co-Authored-By: Claude Opus 4.8 <noreply@anthropic.com>
69 lines
3.0 KiB
Plaintext
69 lines
3.0 KiB
Plaintext
==============================================================================
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VARIATION: naive_boxa_d0_5 [metric: success RATE (success/attempts)]
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==============================================================================
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model: behavior ~ stim + day + stim:day + (1|rat) (behavior = success RATE (success/attempts))
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day = training day within window (0 = first analyzed day)
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treatment (stim=1): Electrode-Box-B2
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control (stim=0): Electrode-Box-A, Electrode-Box-A2, Naive
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N = 11 rats, 63 sessions raw day coverage: treat 0..5, control 0..5
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(equal day coverage over this window)
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==============================================================================
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FULL MODEL SUMMARY -- fitlme
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==============================================================================
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Linear mixed-effects model fit by ML
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Model information:
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Number of observations 63
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Fixed effects coefficients 4
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Random effects coefficients 11
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Covariance parameters 2
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Formula:
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behavior ~ 1 + day*stim + (1 | rat)
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Model fit statistics:
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AIC BIC LogLikelihood Deviance
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-89.552 -76.693 50.776 -101.55
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Fixed effects coefficients (95% CIs):
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Name Estimate SE tStat DF
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{'(Intercept)'} 0.20761 0.03353 6.1919 59
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{'day' } 0.035262 0.0090474 3.8975 59
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{'stim' } -0.042773 0.060953 -0.70173 59
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{'day:stim' } 0.057126 0.016495 3.4631 59
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pValue Lower Upper
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6.1978e-08 0.14052 0.27471
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0.000251 0.017158 0.053365
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0.4856 -0.16474 0.079194
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0.0010002 0.024119 0.090133
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Random effects covariance parameters (95% CIs):
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Group: rat (11 Levels)
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Name1 Name2 Type Estimate
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{'(Intercept)'} {'(Intercept)'} {'std'} 0.050413
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Lower Upper
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0.02388 0.10643
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Group: Error
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Name Estimate Lower Upper
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{'Res Std'} 0.099938 0.082348 0.12129
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effect t(df) / F(df1) p (resid) Satterthwaite: p (df)
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----------------------------------------------------------------------------
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stim x day (interaction) t(59)= 3.46 F(1)= 11.993 p=0.001 p=0.00108 (df=52)
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day (learning) t(59)= 3.90 F(1)= 15.190 p=0.000251 p=0.0002756 (df=53)
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stim (main, window start) t(59)= -0.70 F(1)= 0.492 p=0.4856 p=0.4879 (df=32)
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interaction 95% CI: [+0.02412, +0.09013]
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HONEST LME (per-animal random slope, day|rat): interaction F(1,12.0)=9.63, p=0.009127
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(Satterthwaite DF ~= residual on this random-intercept model; the random-slope
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model above is the honest learning-rate test -- DF collapses toward the animal count.)
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INTERPRETATION: stim x day interaction SIGNIFICANT positive -- treatment improves FASTER (benefit accumulates) (p=0.001, slope diff=+0.05713)
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Paper (N=24, count): interaction t(227)=2.68, F(1)=7.12, p=0.008.
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