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Experiments DB Dev 8a18c894dd feat(matlab): add Satterthwaite DF + honest random-slope test to LME reports
Every fitlme-based report (lme_*, paper_*, phase_*, and the variations'
analyze.m) now shows, per effect: residual-DF p, Satterthwaite-DF p, and --
for the interaction -- an HONEST test from a per-animal random-SLOPE model
(day|rat), whose Satterthwaite DF collapses toward the animal count.

New: tdcs_random_slope_interaction.m (shared helper). Wired into tdcs_lme,
tdcs_paper_lme, tdcs_phase_lme, variation_analyze; SUMMARY.csv gains
interaction_p_satt / interaction_p_rs. Regenerated all results/, variations/,
matched-effort outputs.

Key point this surfaces: Satterthwaite ~= residual on the random-INTERCEPT
model (the slope's error is at session level), so it does NOT fix
pseudoreplication; the random-slope model does. Effect: full-range mergeA2
interaction 0.009 -> 0.75 (collapses); unmerge_d0_5 0.015 -> 0.13 (n.s.);
the pooled-control early windows survive honestly (naive_a2_d0_5 0.001 ->
0.028; naive_boxa_d0_5 0.003 -> 0.036). Suite 42/42.

Co-Authored-By: Claude Opus 4.8 <noreply@anthropic.com>
2026-07-22 15:45:19 -04:00

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==============================================================================
VARIATION: naive_boxa_d0_5
==============================================================================
model: behavior ~ stim + day + stim:day + (1|rat) (behavior = success COUNT)
day = training day within window (0 = first analyzed day)
treatment (stim=1): Electrode-Box-B2
control (stim=0): Electrode-Box-A, Electrode-Box-A2, Naive
N = 11 rats, 65 sessions raw day coverage: treat 0..5, control 0..5
(equal day coverage over this window)
==============================================================================
FULL MODEL SUMMARY -- fitlme
==============================================================================
Linear mixed-effects model fit by ML
Model information:
Number of observations 65
Fixed effects coefficients 4
Random effects coefficients 11
Covariance parameters 2
Formula:
behavior ~ 1 + day*stim + (1 | rat)
Model fit statistics:
AIC BIC LogLikelihood Deviance
540.21 553.25 -264.1 528.21
Fixed effects coefficients (95% CIs):
Name Estimate SE tStat DF pValue
{'(Intercept)'} 8.2006 4.622 1.7743 61 0.081011
{'day' } 8.8157 1.0827 8.1421 61 2.5062e-11
{'stim' } 1.3073 8.7275 0.1498 61 0.88142
{'day:stim' } 6.4033 2.0341 3.1479 61 0.0025447
Lower Upper
-1.0416 17.443
6.6507 10.981
-16.144 18.759
2.3358 10.471
Random effects covariance parameters (95% CIs):
Group: rat (11 Levels)
Name1 Name2 Type Estimate
{'(Intercept)'} {'(Intercept)'} {'std'} 9.1032
Lower Upper
5.2068 15.915
Group: Error
Name Estimate Lower Upper
{'Res Std'} 12.477 10.33 15.071
effect t(df) / F(df1) p (resid) Satterthwaite: p (df)
----------------------------------------------------------------------------
stim x day (interaction) t(61)= 3.15 F(1)= 9.909 p=0.002545 p=0.002679 (df=54)
day (learning) t(61)= 8.14 F(1)= 66.293 p=2.506e-11 p=5.765e-11 (df=54)
stim (main, window start) t(61)= 0.15 F(1)= 0.022 p=0.8814 p=0.8822 (df=24)
interaction 95% CI: [+2.34, +10.47]
HONEST LME (per-animal random slope, day|rat): interaction F(1,10.5)=5.80, p=0.03561
(Satterthwaite DF ~= residual on this random-intercept model; the random-slope
model above is the honest learning-rate test -- DF collapses toward the animal count.)
INTERPRETATION: stim x day interaction SIGNIFICANT positive -- treatment improves FASTER (benefit accumulates) (p=0.002545, slope diff=+6.40)
Paper (N=24): interaction t(227)=2.68, F(1)=7.12, p=0.008.