analysis(matlab): Box-A pooling variations (b2 vs a2+a, b2+a vs a2)

Add make_boxa_variations.m producing 6 variation folders (data.csv + analyze.m
+ result.txt) for the paper LME over windows 0-5, 6-10, 0-10:
  boxa_a2  B2         vs A2 + Box-A   (b2 vs a2+a)
  boxa_b2  B2 + Box-A vs A2           (b2+a vs a2)
plus variations/boxa_summary.csv (residual / Satterthwaite / random-slope
interaction p). Early window (0-5) is obs-level significant (res p~0.03-0.04)
but n.s. under the honest random-slope test (rs p~0.13); later windows n.s.

Co-Authored-By: Claude Opus 4.8 <noreply@anthropic.com>
This commit is contained in:
Experiments DB Dev
2026-07-23 13:39:01 -04:00
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==============================================================================
VARIATION: boxa_a2_d0_5
==============================================================================
model: behavior ~ stim + day + stim:day + (1|rat) (behavior = success COUNT)
day = training day within window (0 = first analyzed day)
treatment (stim=1): Electrode-Box-B2
control (stim=0): Electrode-Box-A, Electrode-Box-A2
N = 7 rats, 42 sessions raw day coverage: treat 0..5, control 0..5
(equal day coverage over this window)
==============================================================================
FULL MODEL SUMMARY -- fitlme
==============================================================================
Linear mixed-effects model fit by ML
Model information:
Number of observations 42
Fixed effects coefficients 4
Random effects coefficients 7
Covariance parameters 2
Formula:
behavior ~ 1 + day*stim + (1 | rat)
Model fit statistics:
AIC BIC LogLikelihood Deviance
339.96 350.39 -163.98 327.96
Fixed effects coefficients (95% CIs):
Name Estimate SE tStat DF pValue
{'(Intercept)'} 10.06 4.3445 2.3155 38 0.026083
{'day' } 10.543 1.4349 7.3472 38 8.3775e-09
{'stim' } -0.55159 6.6363 -0.083116 38 0.9342
{'day:stim' } 4.6762 2.1919 2.1334 38 0.03941
Lower Upper
1.2645 18.855
7.638 13.448
-13.986 12.883
0.2389 9.1135
Random effects covariance parameters (95% CIs):
Group: rat (7 Levels)
Name1 Name2 Type Estimate
{'(Intercept)'} {'(Intercept)'} {'std'} 0
Lower Upper
NaN NaN
Group: Error
Name Estimate Lower Upper
{'Res Std'} 12.006 9.6941 14.868
effect t(df) / F(df1) p (resid) Satterthwaite: p (df)
----------------------------------------------------------------------------
stim x day (interaction) t(38)= 2.13 F(1)= 4.551 p=0.03941 p=0.03878 (df=42)
day (learning) t(38)= 7.35 F(1)= 53.982 p=8.377e-09 p=4.651e-09 (df=42)
stim (main, window start) t(38)= -0.08 F(1)= 0.007 p=0.9342 p=0.9342 (df=42)
interaction 95% CI: [+0.24, +9.11]
HONEST LME (per-animal random slope, day|rat): interaction F(1,7.0)=2.87, p=0.1341
(Satterthwaite DF ~= residual on this random-intercept model; the random-slope
model above is the honest learning-rate test -- DF collapses toward the animal count.)
INTERPRETATION: stim x day interaction SIGNIFICANT positive -- treatment improves FASTER (benefit accumulates) (p=0.03941, slope diff=+4.68)
Paper (N=24): interaction t(227)=2.68, F(1)=7.12, p=0.008.