analysis(matlab): matched-effort comparison (prev _f full vs current 0-3)
Add make_matched_effort.m: pick the current-study day cutoff whose per-animal cumulative attempts best match the previous (_f) study's full-span total (~405 attempts/animal -> current days 0-3), then fit the paper LME on both. Two variation folders (data.csv + analyze.m + result.txt): variations/prev_f_full/ b2_f vs a2_f, days 0-9 (24 rats) variations/matched_current_d0_3/ Box-B2 vs Box-A2, 0-3 (6 rats) At matched cumulative effort both show a significant positive stim x day interaction (prev p=0.008 +0.56/day; current-0-3 p=0.004 +10.2/day) -- the tDCS acceleration replicates at equal practice, though the count slopes are not directly comparable across datasets given differing attempts/session. Co-Authored-By: Claude Opus 4.8 <noreply@anthropic.com>
This commit is contained in:
@@ -0,0 +1,65 @@
|
||||
==============================================================================
|
||||
VARIATION: matched_current_d0_3
|
||||
==============================================================================
|
||||
model: behavior ~ stim + day + stim:day + (1|rat) (behavior = success COUNT)
|
||||
day = training day within window (0 = first analyzed day)
|
||||
treatment (stim=1): Electrode-Box-B2
|
||||
control (stim=0): Electrode-Box-A2
|
||||
N = 6 rats, 24 sessions raw day coverage: treat 0..3, control 0..3
|
||||
(equal day coverage over this window)
|
||||
|
||||
==============================================================================
|
||||
FULL MODEL SUMMARY -- fitlme
|
||||
==============================================================================
|
||||
|
||||
Linear mixed-effects model fit by ML
|
||||
|
||||
Model information:
|
||||
Number of observations 24
|
||||
Fixed effects coefficients 4
|
||||
Random effects coefficients 6
|
||||
Covariance parameters 2
|
||||
|
||||
Formula:
|
||||
behavior ~ 1 + day*stim + (1 | rat)
|
||||
|
||||
Model fit statistics:
|
||||
AIC BIC LogLikelihood Deviance
|
||||
185.35 192.42 -86.676 173.35
|
||||
|
||||
Fixed effects coefficients (95% CIs):
|
||||
Name Estimate SE tStat DF pValue
|
||||
{'(Intercept)'} 16.867 4.4554 3.7856 20 0.0011608
|
||||
{'day' } 6.3667 2.2049 2.8875 20 0.0091051
|
||||
{'stim' } -8.9667 6.3009 -1.4231 20 0.17013
|
||||
{'day:stim' } 10.2 3.1182 3.2711 20 0.0038217
|
||||
|
||||
|
||||
Lower Upper
|
||||
7.5728 26.161
|
||||
1.7673 10.966
|
||||
-22.11 4.1769
|
||||
3.6955 16.705
|
||||
|
||||
Random effects covariance parameters (95% CIs):
|
||||
Group: rat (6 Levels)
|
||||
Name1 Name2 Type Estimate
|
||||
{'(Intercept)'} {'(Intercept)'} {'std'} 2.9163
|
||||
|
||||
|
||||
Lower Upper
|
||||
0.43116 19.725
|
||||
|
||||
Group: Error
|
||||
Name Estimate Lower Upper
|
||||
{'Res Std'} 8.5397 6.1599 11.839
|
||||
|
||||
|
||||
effect t (df) F (df1) p
|
||||
------------------------------------------------------------------
|
||||
stim x day (interaction) t(20)= 3.27 F(1)= 10.700 p=0.003822
|
||||
day (learning) t(20)= 2.89 F(1)= 8.337 p=0.009105
|
||||
stim (main, window start) t(20)= -1.42 F(1)= 2.025 p=0.1701
|
||||
interaction 95% CI: [+3.70, +16.70]
|
||||
INTERPRETATION: stim x day interaction SIGNIFICANT positive -- treatment improves FASTER (benefit accumulates) (p=0.003822, slope diff=+10.20)
|
||||
Paper (N=24): interaction t(227)=2.68, F(1)=7.12, p=0.008.
|
||||
Reference in New Issue
Block a user